You should not have any troubles in Brussels. A lot of people speak English. it's a very cosmopolitan city (because so many International institution have their seat there) and in the touristic area, people HAVE to speak English.
There are flights from Brussels to London. SN-Airlines, British Airways, British Midland, Lufthansa... I saw that a one-way from Brussels to London with SN Airlines was 85 US$. Of course, it depends when you leave.
You can have a Eurostar ticket for as little as 45 US$ but there are a lot of restriction (like you have to leave on certains days, during certain time an spend a night in London or buy a return ticket -which probably doesn't help you)...
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